Causality in medicine

Causality and medicine.

The philosophers of science who viewed causality as a metaphysical headache were right. Yet when they concluded that it is of no scientific import and of less practical import, they were clearly in error. I say clearly because they thereby recommended that we replace cause by mere empirical correlation, which obviously will not do. Here is an obvious example which proves them in error without e...

Epistemic causality and evidence-based medicine.

Causal claims in biomedical contexts are ubiquitous albeit they are not always made explicit. This paper addresses the question of what causal claims mean in the context of disease. It is argued that in medical contexts causality ought to be interpreted according to the epistemic theory. The epistemic theory offers an alternative to traditional accounts that cash out causation either in terms o...

On the notion of causality in medicine: addressing

Almost 50 years ago appeared the seminal article by Austin Bradford Hill where he presented parameters for inferring causes from statistical associations, which became known as Hill’s causal criteria. This was a milestone for the renewal of the idea of cause in medicine. Our article revisits his contribution in light of the ideas from the Australian philosopher John L. Mackie, whose important w...

Causality at the dawn of the 'omics' era in medicine and in nephrology.

Causality is a core concept in medicine. The quantitative determinacy characterizing today's biomedical science is unprecedented. The assessment of causal relations in human diseases is evolving, and it is therefore fundamental to keep up with the steady pace of theoretical and technological advancements. The exact specification of all causes of pathologies at the individual level, precision me...

Causality